Dihydroxylation of 2-vinylaziridine: efficient synthesis of D-ribo-phytosphingosine.
نویسندگان
چکیده
An efficient and highly stereoselective synthesis of D-ribo-(2S,3S,4R)-phytosphingosine was accomplished in 62% overall yield starting from commercially available (2S)-hydroxymethylaziridine via osmium-catalyzed asymmetric dihydroxylation as a key step.
منابع مشابه
Chemical synthesis of D-ribo-phytosphingosine-1-phosphate, a potential modulator of cellular processes.
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عنوان ژورنال:
- Chemical communications
دوره 1 شماره
صفحات -
تاریخ انتشار 2007